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Prospective study of objective physical activity and quality of life in living donor liver transplant recipients
Author(s) -
Tanaka Satomi,
Fujita Kimie,
Kanaoka Maki,
Makimoto Kiyoko,
Yakushiji Kanako,
Tanaka Rumi,
Harada Noboru,
Ikegami Toru,
Yoshizumi Tomoharu
Publication year - 2020
Publication title -
japan journal of nursing science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.363
H-Index - 17
eISSN - 1742-7924
pISSN - 1742-7932
DOI - 10.1111/jjns.12362
Subject(s) - medicine , quality of life (healthcare) , psychological intervention , multivariate analysis , physical activity , physical therapy , liver transplantation , living donor liver transplantation , health related quality of life , transplantation , disease , nursing , psychiatry
Aim The aims of this study were to: (a) describe the physical activity (PA) and quality of life (QOL) in living donor liver transplant (LDLT) recipients pre‐operatively and at 3 months and 6 months post‐operatively; (b) compare PA and QOL at 6 months post‐operatively with a healthy control group; and (c) explore pre‐operative factors that predict PA changes. Methods Patients over 20 years of age who were undergoing LDLT were recruited. PA was measured based on the number of steps/day and time spent performing moderate‐to‐vigorous PA (MVPA) during 1 week using an accelerometer. QOL was assessed based on a physical (PCS) and mental (MCS) component summary of the eight‐item Short‐Form Health Survey. The LDLT and healthy control groups were matched for age (±3 years) and gender. Pre‐operative factors predicting a change in PA were calculated using a generalized linear mixed model. Results Twenty‐four patients completed the study. By 6 months post‐LDLT, the MCS and PCS were comparable to those in the control group. The number of steps (3,887 steps/day) and MVPA (29.3 min/week) showed significant improvement by 6 months post‐operatively, but remained much lower compared with those in the control group. The multivariate analysis showed that younger age ( p < .01, p = .04) and higher skeletal muscle mass (SMM; p < .01, p = .03) were predictors of improvement in number of steps and MVPA. Conclusion This study suggests the need for pre‐operative interventions by healthcare professionals that focus on outcomes such as improving low SMM to facilitate post‐operative PA recovery.