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Cover Image: AtSec62 located in autophagosome
Publication year - 2020
Publication title -
journal of integrative plant biology
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 2.734
H-Index - 83
eISSN - 1744-7909
pISSN - 1672-9072
DOI - 10.1111/jipb.12908
Subject(s) - endoplasmic reticulum , unfolded protein response , microbiology and biotechnology , translocon , arabidopsis , homeostasis , folding (dsp implementation) , protein folding , autophagosome , chemistry , biology , autophagy , membrane protein , membrane , biochemistry , gene , engineering , apoptosis , mutant , electrical engineering
Endoplasmic reticulum (ER) is the major site for protein synthesis and protein folding. The ER quality control system (ERQC) plays pivotal role in ER homeostasis. In this study, Hu et al. (pp. 181–200) demonstrated that AtSec62, an ER membrane‐localized protein and a component of the Sec translocon system, is critical for keeping ER homeostasis under ER stress condition in plants. Under ER stress condition, GFP‐tagged AtSec62 forms ring like autophagosomal structures to alleviate ER stress via ER‐phagy in Arabidopsis transgenic plants.