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Arabidopsis Forkhead‐Associated Domain Protein 3 negatively regulates peroxisome division
Author(s) -
Desai Mintu,
Pan Ronghui,
Hu Jianping
Publication year - 2017
Publication title -
journal of integrative plant biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.734
H-Index - 83
eISSN - 1744-7909
pISSN - 1672-9072
DOI - 10.1111/jipb.12542
Subject(s) - arabidopsis , forkhead transcription factors , division (mathematics) , microbiology and biotechnology , domain (mathematical analysis) , biology , genetics , gene , transcription factor , mathematics , mutant , mathematical analysis , arithmetic
Summary Peroxisomes are ubiquitous and dynamic eukaryotic organelles capable of altering their abundance in response to environmental and developmental cues, yet the regulatory mechanism of plant peroxisome division/proliferation is unclear. To identify transcriptional regulators of the peroxisome division factor gene PEX11b , we performed a nuclear pull‐down experiment and identified Arabidopsis Forkhead‐Associated Domain Protein 3 (FHA3) as a novel protein that binds to the promoter of PEX11b . Our data supported the conclusion that, in contrast to the previously identified HY5 HOMOLOG (HYH) protein that promotes the transcription of PEX11b , FHA3 is a negative regulator of PEX11b expression and peroxisome division.