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Plant Mediator complex and its critical functions in transcription regulation
Author(s) -
Yang Yan,
Li Ling,
Qu LiJia
Publication year - 2016
Publication title -
journal of integrative plant biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.734
H-Index - 83
eISSN - 1744-7909
pISSN - 1672-9072
DOI - 10.1111/jipb.12377
Subject(s) - mediator , biology , rna polymerase ii , transcription (linguistics) , transcription factor , microbiology and biotechnology , general transcription factor , genetics , computational biology , gene , promoter , gene expression , linguistics , philosophy
The Mediator complex is an important component of the eukaryotic transcriptional machinery. As an essential link between transcription factors and RNA polymerase II, the Mediator complex transduces diverse signals to genes involved in different pathways. The plant Mediator complex was recently purified and comprises conserved and specific subunits. It functions in concert with transcription factors to modulate various responses. In this review, we summarize the recent advances in understanding the plant Mediator complex and its diverse roles in plant growth, development, defense, non‐coding RNA production, response to abiotic stresses, flowering, genomic stability and metabolic homeostasis. In addition, the transcription factors interacting with the Mediator complex are also highlighted.