Open AccessNon‐oral, aerobic, Gram‐negative bacilli in the oral cavity of Thai HIV ‐positive patients on Highly‐active anti‐retrovirus therapy medication
Author(s) -
Arirachakaran Pratanporn,
Luangworakhun Sureeat,
Charalampakis Georgios,
Dahlén Gunnar
Publication year - 2019
Publication title -
journal of investigative and clinical dentistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.599
H-Index - 21
eISSN - 2041-1626
pISSN - 2041-1618
DOI - 10.1111/jicd.12387
Subject(s) - microbiology and biotechnology , clindamycin , pseudomonas aeruginosa , ciprofloxacin , penicillin , biology , amoxicillin , aeromonas hydrophila , antibiotics , virology , medicine , bacteria , genetics
In the present study, we identified and evaluated the antibiotic susceptibility of 96 independent, aerobic, Gram‐negative bacillus isolates from 255 Thai HIV ‐positive adults who were on Highly‐active anti‐retrovirus therapy (HAART) medication. Another 46 isolates from HIV non‐ HAART individuals, vertically transmitted HIV ‐positive individuals, and non‐ HIV controls were included for comparison. A total of 103 strains were tested for antibiotic susceptibility using disc diffusion for screening and E‐test for minimal inhibitory concentration determination, with special attention on extended‐spectrum beta‐lactamase ( ESBL ) isolates. Pseudomonas aeruginosa , Pseudomonas luteola , Burkholderia cepacia , Aeromonas hydrophila , Klebsiella , and Enterobacter species were the most common bacteria. All strains were resistant against penicillin, amoxicillin, clindamycin, and metronidazole. No ESBL isolates were found.