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Mexican‐American Dementia Nomogram: Development of a Dementia Risk Index for Mexican‐American Older Adults
Author(s) -
Downer Brian,
Kumar Amit,
Veeranki Sreenivas P.,
Mehta Hemalkumar B.,
Raji Mukaila,
Markides Kyriakos S.
Publication year - 2016
Publication title -
journal of the american geriatrics society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.992
H-Index - 232
eISSN - 1532-5415
pISSN - 0002-8614
DOI - 10.1111/jgs.14531
Subject(s) - dementia , medicine , gerontology , nomogram , population , confidence interval , activities of daily living , cohort study , physical therapy , environmental health , disease
Objectives To create a risk index (Mexican American Dementia Nomogram ( MAD eN)) that predicts dementia over a 10‐year period for Mexican Americans aged 65 and older. Design Retrospective cohort study with longitudinal analysis. Setting Texas, New Mexico, Colorado, Arizona, and California. Participants Hispanic Established Populations for the Epidemiologic Study of the Elderly (H‐ EPESE ) participants (n = 1,739). Measurements Dementia was defined as a decline of three or more points per year on the Mini‐Mental State Examination and inability to perform one or more daily activities. Candidate risk factors included demographic characteristics, measures of social engagement, self‐reported health conditions, ability to perform daily activities, and physical activity. Results The MAD eN comprised the following risk factors: age, sex, education, not having friends to count on, not attending community events, diabetes mellitus, feeling the blues, pain, impairment in instrumental activities of daily living, and unable to walk a half‐mile. The area under the receiver operating characteristic curve was 0.74 (95% confidence interval ( CI ) = 0.70–0.78) and a score of 16 points or higher had a sensitivity of 0.65 (95% CI = 0.59–0.72) and specificity of 0.70 (95% CI = 0.67–0.73) in predicting dementia. Conclusion The MAD eN was able to predict dementia in a population of older Mexican‐American adults with moderate accuracy. It has the potential to identify older Mexican‐American adults who may benefit from interventions to reduce dementia risk and to educate this population about risk factors for dementia.

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