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Association Between Serum 25‐Hydroxyvitamin D Concentration and Optic Chiasm Volume
Author(s) -
Annweiler Cédric,
Beauchet Olivier,
Bartha Robert,
Graffe Alix,
Milea Dan,
MonteroOdasso Manuel
Publication year - 2013
Publication title -
journal of the american geriatrics society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.992
H-Index - 232
eISSN - 1532-5415
pISSN - 0002-8614
DOI - 10.1111/jgs.12249
Subject(s) - medicine , optic chiasm , association (psychology) , volume (thermodynamics) , ophthalmology , optic nerve , philosophy , physics , epistemology , quantum mechanics
To the Editor: Vitamin D has multiple nonskeletal effects. In particular, low serum 25-hydroxyvitamin D (25OHD) concentrations are associated with poor visual acuity in older adults. This association has been tentatively explained by the onset of age-related macular degeneration (AMD) in the case of hypovitaminosis D, but no causal relationship has been established, and other hypotheses have not been tested. For instance, because vitamin D is involved in neurophysiology and neuroprotection, it was hypothesized that low 25OHD concentrations could result in optic neuropathy. The optic chiasm is the union of the optic nerves and gives rise to the optic tracts, which synapse in the gray matter of the thalamus. The objective of the current study was to determine whether serum 25OHD concentrations were associated with the volume of the optic chiasm in community-dwelling older adults.