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E‐Poster Presentations – A2) Gastric and Duodenal
Author(s) -
HUY TRAN VAN,
HAI NGUYEN THANH,
KHOA LE NGUYEN DANG,
JIAN LIU
Publication year - 2017
Publication title -
journal of gastroenterology and hepatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.214
H-Index - 130
eISSN - 1440-1746
pISSN - 0815-9319
DOI - 10.1111/jgh.13875
Subject(s) - medicine , gastroenterology , general surgery
Background: Combination of antiplatelet drugs, antithrombotic drugs, and coronary reperfusion intervention including firinolytic drugs and percutaneous coronary intervention (PCI) increases gastrointestinal (GI) bleeding risk in pts with MI. GI bleeding is the most common noncardiac complication in pts with MI, particularly MI pts having PCI. GI bleeding increases mortality rate as well as length of hospitalization and cost in pts with MI. Actually, we don’t have yet lots of researches on this problem. Therefore, we aimed to identify prevalence of non-variceal GI bleeding, risk factors of non-variceal GI bleeding, length of hospitalization, and mortality rate in hospital in pts with acute MI. Methods: Retrospective study was conducted. We collected research data from archive room at Gia Dinh People Hospital. ICD codes consisted of I21, I21.4, and I21.9. We gathered research information according to data sheet. Univariable and multivariable logistic regression identified risk factors of GI bleeding in pts with acute MI. Results: We collected 351 pts with acute MI hospitalized at Gia Dinh People Hospital from January 2011 to December 2012. GI bleeding event accounted for 8.3%. Risk factors of GI bleeding included history of epigastric pain OR = 25.6 (4.5–146.6) with p = 0.001, history of peptic ulcer OR = 7.4 (2.5–21.7) with p = 0.001, and history of using NSAIDs OR = 9.2 (1.9–43.2) with p = 0.014. In multivariable analysis, only 2 out of 3 above risk factors were significant including history of epigastric pain (p < 0.0001) and history of peptic ulcer (p = 0.01). Length of hospitalization in pts with GI bleeding lasted longer than in pts without GI bleeding (11.59 ± 5.93 days vs 7.71 ± 5.29 days) p < 0.0001. Pts with GI bleeding had higher mortality rate than patients with GI bleeding 17.2% vs 11.2%, respectively (p = 0.361). Conclusion: Pts with acute MI have high rate of GI bleeding event. In clinical practice, some important factors in medical history need to be taken to predict risk of GI bleeding in pts with acute MI.