Survival of patients with gastric lymphoma in G ermany and in the U nited S tates

Background and Aim This study aims to examine survival for gastric lymphomas and its main subtypes, mucosa‐associated lymphoid tissue lymphoma ( MALT ), and diffuse large B ‐cell lymphoma ( DLBCL ), in G ermany and in the U nited S tates. Methods Data for patients diagnosed in 1997–2010 were used from 10 population‐based G erman cancer registries and compared to the data from the US S urveillance, E pidemiology and E nd R esults ( SEER ) 13 registries database. Patients age 15–74 diagnosed with gastric lymphomas were included in the analysis. Period analysis and modeled period analysis were used to estimate 5‐year and 10‐year relative survival ( RS ) in 2002–2010 and survival trends from 2002–2004 to 2008–2010. Results Overall, the database included 1534 and 2688 patients diagnosed with gastric lymphoma in 1997–2010 in G ermany and in the U nited S tates, respectively. Survival was substantially higher for MALT (5‐year and 10‐year RS : 89.0% and 80.9% in G ermany, 93.8% and 86.8% in the U nited S tates) than for DLBCL (67.5% and 59.2% in G ermany, and 65.3% and 54.7% in the U nited S tates) in 2002–2010. Survival was slightly higher among female patients and decreased by age for gastric lymphomas combined and its main subtypes. A slight, nonsignificant, increase in the 5‐year RS for gastric lymphomas combined was observed in G ermany and the U nited S tates, with increases in 5‐year RS between 2002–2004 and 2008–2010 from 77.1% to 81.0% and from 77.3% to 82.0%, respectively. Five‐year RS of MALT exceeded 90% in 2008–2010 in both countries. Conclusions Five‐year RS of MALT meanwhile exceeds 90% in both G ermany and the United States, but DLBCL has remained below 70% in both countries.