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Surveillance of short‐segment B arrett's esophagus using ultrathin transnasal endoscopy
Author(s) -
Sugimoto Hiroko,
Kawai Takashi,
Naito Sakiko,
Yanagizawa Kyosuke,
Yamagishi Tetsuya,
Fukuzawa Masakatsu,
Yagi Kenji,
Matsubayashi Jun,
Nagao Toshitaka,
Tomiyama Hirofumi,
Hoshino Sumito,
Tsuchida Akihiko,
Moriyasu Fuminori
Publication year - 2015
Publication title -
journal of gastroenterology and hepatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.214
H-Index - 130
eISSN - 1440-1746
pISSN - 0815-9319
DOI - 10.1111/jgh.12879
Subject(s) - esophagus , medicine , intestinal metaplasia , endoscopy , barrett's esophagus , metaplasia , endoscope , anatomy , pathology , gastroenterology , radiology , adenocarcinoma , stomach , cancer
Abstract Background and Aim Newly developed ultrathin transnasal endoscope, the GIF ‐ XP290N , makes possible a resolving power similar to the GIF ‐ H260 at a distance of 3 mm. We conducted surveillance of subjects with B arrett's esophagus using this ultrathin transnasal endoscopy. In Japan the lower margin of the lower esophageal palisade vessels is defined the gastroesophageal junction in deep inspiration. We diagnose Barrett's esophagus if columnar epithelium is present on the oral side of the gastroesophageal junction. Methods and Results B arrett's esophagus was confirmed in 116 out of 135 subjects (85.9%), with 17 cases of short‐segment B arrett's esophagus ( SSBE ) and 99 of ultra‐short‐segment Barrett's esophagus. Close observation of the B arrett's esophagus mucosal structural pattern using narrow band imaging revealed 29 cases with an oval or round pattern, 29 with a long straight pattern, 47 with a villous pattern, 8 with a cerebriform pattern, and 6 with an irregular pattern according to Goda classification. Mucosal biopsies from all subjects with SSBE are examined. Histological examination revealed intestinal metaplasia in only eight subjects. We grouped the oval/round and long straight patterns as closed type, and the villous, cerebriform, and irregular patterns as open type. Analysis of the relationship between these mucosal patterns and background factors revealed a significant correlation between intestinal metaplasia and the open‐type pattern. Conclusion We consider this new ultrathin transnasal endoscopy to be a useful technique for surveillance of Barrett's esophagus, especially SSBE .