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Magnetic resonance enterocolonography in detecting erosion and redness in intestinal mucosa of patients with C rohn's disease
Author(s) -
Sato Hirokazu,
Tamura Chiharu,
Narimatsu Kazuyuki,
Shimizu Motonori,
Takajyo Takeshi,
Yamashita Masataka,
Inoue Yasushi,
Ozaki Hayato,
Furuhashi Hirotaka,
Maruta Koji,
Yasutake Yuichi,
Yoshikawa Kenichi,
Watanabe Chikako,
Komoto Shunsuke,
Tomita Kengo,
Nagao Shigeaki,
Miura Soichiro,
Shinmoto Hiroshi,
Hokari Ryota
Publication year - 2015
Publication title -
journal of gastroenterology and hepatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.214
H-Index - 130
eISSN - 1440-1746
pISSN - 0815-9319
DOI - 10.1111/jgh.12851
Subject(s) - medicine , magnetic resonance imaging , endoscopy , lesion , edema , radiology , pathology , gastroenterology
Background and Aim In C rohn's disease ( CD ), assessment of disease activity and extension is important for clinical management. Endoscopy is the most reliable tool for evaluating disease activity in these patients and it distinguishes between lesions based on ulcer, erosion, and redness. Magnetic resonance imaging ( MRI ) is less invasive than endoscopy; however, the sensitivity of MRI in detecting lesions is believed to be lower, and whether MRI can detect milder lesions has not been studied. The aim of this study was to compare the detection ability of magnetic resonance enterocolonography ( MREC ) with ileocolonic endoscopy in patients with CD . Methods A total of 27 patients with CD underwent both MREC and ileocolonoscopy. There were 55 lesions (18 ileum and 37 colon) endoscopically detected, and the findings of MREC were compared with each ileocolonoscopic finding to determine sensitivity and specificity. Results For a positive lesion defined as having at least one of the following: wall thickness, edema, diffusion‐weighted imaging ( DWI ) high intensity and relative contrast enhancement ( RCE ) on MREC , the sensitivities were 100% for ulcer, 84.6% for erosion, and 52.9% for redness, suggesting an ability to detect milder lesions such as erosion or redness. Moreover, RCE values were well correlated with the severity of endoscopically identified active lesions. Conclusion MREC findings may be useful not only for evaluation of ulcers, but also for detection of endoscopically identified milder lesions in CD , suggesting a clinical usefulness of MREC for disease detection and monitoring.