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Risk of adenomas with high‐risk characteristics based on two previous colonoscopy
Author(s) -
Suh KangHeum,
Koo Ja Seol,
Hyun Jong Jin,
Choi Jungsoon,
Han Jang Soo,
Kim Seung Young,
Jung Sung Woo,
Jeen Yoon Tae,
Lee Sang Woo,
Choi Jai Hyun
Publication year - 2014
Publication title -
journal of gastroenterology and hepatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.214
H-Index - 130
eISSN - 1440-1746
pISSN - 0815-9319
DOI - 10.1111/jgh.12650
Subject(s) - colonoscopy , medicine , adenoma , colorectal cancer , hyperplastic polyp , multivariate analysis , gastroenterology , general surgery , cancer
Background and Aim The recommended intervals between surveillance colonoscopies are based on the most recent examination findings. However, whether the two previous colonoscopies affect second surveillance colonoscopic findings is not established. The aim of this study is to estimate the risk of obtaining high‐risk findings ( HRF ) on the next surveillance colonoscopy using the results of two previous colonoscopies, and to estimate the appropriate time interval for the next surveillance colonoscopy. Methods Among subjects who underwent screening colonoscopy during J anuary 2002– D ecember 2009, patients who underwent second surveillance colonoscopy before J une 2012 were enrolled. “No adenoma” was defined as a hyperplastic polyp or no polyp, “low‐risk findings ( LRF )” as one or two small (< 1 cm) tubular adenomas, and “ HRF ” as advanced adenoma, cancer, or any sized multiple (≥ 3) adenomas. Results Among enrolled 852 subjects, 65 (7.6%) had HRF at second surveillance colonoscopy. Multivariate analysis showed that HRF on second surveillance colonoscopy were associated with male and HRF on screening colonoscopy (all, P < 0.01). In subjects with LRF on first surveillance colonoscopy, HRF on the screening colonoscopy significantly affected the detection of HRF on second surveillance colonoscopy ( P < 0.01). Patients with HRF on screening colonoscopy and LRF on the first surveillance colonoscopy had no different risk of HRF on second surveillance colonoscopy from those with HRF on first surveillance colonoscopy ( P > 0.05). Conclusions The HRF on second surveillance are significantly associated with previous two colonoscopic results. In patients with LRF on first surveillance, screening colonoscopic findings should be considered to determine the optimal surveillance interval.