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Association of greater intravenous volume infusion with shorter hospitalization for patients with post‐ERCP pancreatitis
Author(s) -
Sagi Sashidhar V,
Schmidt Suzette,
Fogel Evan,
Lehman Glen A,
McHenry Lee,
Sherman Stuart,
Watkins James,
Coté Gregory A
Publication year - 2014
Publication title -
journal of gastroenterology and hepatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.214
H-Index - 130
eISSN - 1440-1746
pISSN - 0815-9319
DOI - 10.1111/jgh.12511
Subject(s) - medicine , endoscopic retrograde cholangiopancreatography , pancreatitis , retrospective cohort study , demographics , acute pancreatitis , gastroenterology , cohort , surgery , demography , sociology
Background and Aim There are no data specifically correlating early intravenous volume infusion ( IVI ) with the length of hospitalization for postendoscopic retrograde cholangiopancreatography ( ERCP ) pancreatitis ( PEP ). Methods We conducted a retrospective cohort study of patients admitted within 24 h after ERCP to our institute with PEP . IVI during the first 24 h after ERCP was assessed. Primary outcome was severity of PEP , defined by length of hospitalization according to consensus guidelines: mild ≤ 3, moderate 4–10, and severe > 10 days. Results Of 72 eligible patients, 41 (56.9%) had mild and 31 (43.1%) moderate/severe PEP . Both groups had comparable demographics, indications, and procedural factors except patients with moderate/severe PEP were older (median age 49 vs 36 years, P = 0.05) and more likely to be discharged and readmitted within the first 24 h (41.9% vs 14.6%, P < 0.01). Patients with mild PEP received significantly greater IVI during the first 24 h (2834 mL [2046, 3570] vs 2044 mL [1227, 2875], P < 0.02) and 50% more fluid post‐ ERCP (2270 mL [1435, 2961] vs 1515 [950–2350], P < 0.02) compared with those with at least moderate PEP . Conclusion In patients with PEP , greater IVI during the first 24 h after ERCP is associated with reduced length of hospitalization. Lower IVI was more commonly observed in individuals who were discharged and then readmitted during the first 24 h.