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High sensitivity of quick view capsule endoscopy for detection of small bowel C rohn's disease
Author(s) -
Halling Morten Lee,
Nathan Torben,
Kjeldsen Jens,
Jensen Michael Dam
Publication year - 2014
Publication title -
journal of gastroenterology and hepatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.214
H-Index - 130
eISSN - 1440-1746
pISSN - 0815-9319
DOI - 10.1111/jgh.12488
Subject(s) - medicine , capsule endoscopy , endoscopy , capsule , gastroenterology , disease , radiology , botany , biology
Background and Aim Capsule endoscopy ( CE ) has a high sensitivity for diagnosing small bowel C rohn's disease, but video analysis is time‐consuming. The quick view (qv) function is an effective tool to reduce time consumption. The aim of this study was to determine the rate of missed small bowel ulcerations with qv‐ CE compared with standard view and the diagnostic accuracy of qv‐ CE in suspected C rohn's disease. Methods This study consisted of two parts: (i) 12 small bowel segments with C rohn's disease of varying severity were selected for a detailed analysis of the number and type of lesions visualized with CE and qv‐ CE , and (ii) a blinded study of the diagnostic accuracy of qv‐ CE including 40 patients with suspected C rohn's disease. Ileocolonoscopy and CE served as gold standard. Results Part 1: CE visualized 171 ulcerations compared with 102 detected with qv‐ CE (miss rate 40%, P = 0.02). Part 2: qv‐ CE identified 15 of 16 patients with small bowel C rohn's disease corresponding to a 94% sensitivity, and overall, 39 out of 40 patients were classified correct (diagnostic accuracy 98%). Qv‐ CE was false negative in one patient because of a leap of 3 min and 20 s in the terminal ileum. Reading times varied from 5 to 18 min (median 10). Conclusion Despite a significant number of missed lesions, qv‐ CE is a safe and time‐reducing method for diagnosing small bowel C rohn's disease. To avoid false negative cases, we recommend viewing the terminal ileum in standard view.