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Use of capsule endoscopy in patients with C rohn's disease in J apan: A multicenter survey
Author(s) -
Esaki Motohiro,
Matsumoto Takayuki,
Watanabe Kenji,
Arakawa Tetsuo,
Naito Yuji,
Matsuura Minoru,
Nakase Hiroshi,
Hibi Toshifumi,
Matsumoto Takayuki,
Nouda Sadaharu,
Higuchi Kazuhide,
Ohmiya Naoki,
Goto Hidemi,
Kurokawa Sei,
Motoya Satoshi,
Watanabe Mamoru
Publication year - 2014
Publication title -
journal of gastroenterology and hepatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.214
H-Index - 130
eISSN - 1440-1746
pISSN - 0815-9319
DOI - 10.1111/jgh.12411
Subject(s) - medicine , capsule endoscopy , ileitis , gastroenterology , capsule , lesion , disease , crohn's disease , endoscopy , colitis , inflammatory bowel disease , surgery , botany , biology
Background and Aim Until the approval of patency capsule, capsule endoscopy ( CE ) has not been routinely applied for the diagnosis of C rohn's disease ( CD ) in J apan. We aimed to survey current situation of CE use for patients with CD in J apan. Methods The nationwide survey of 40 J apanese institutions identified 94 patients with established CD (e CD ) and 80 patients with suspected CD (s CD ), who were examined by CE . Types and positive rates of mucosal injury under CE and capsule retention rate were investigated. In s CD , final diagnosis after CE was also analyzed. Results Patients with e CD comprised 82 patients of ileitis or ileocolitis type, while 12 patients had CD of colitis type. CE identified mucosal injuries in 83 of 94 patients. Eight of 12 patients with e CD of colitis type had ileal lesions under CE , thereby being reclassified as ileocolitis type. In patients with s CD , CE detected mucosal injuries in 58 patients. Linear ulceration and cobblestone appearance were depicted in 22 and 3 patients, respectively, thereby resulting in established diagnosis of CD in 23 patients. Mucosal lesion was not found in 22 patients with s CD , who were diagnosed as not having CD . Capsule retention rate was not statistically different between patients with e CD and those with s CD (7.4% vs 6.3%, P = 1.0). Conclusions CE is useful for the evaluation of small bowel mucosal injuries in J apanese patients with s CD and e CD . Possible intestinal stricture needs to be carefully evaluated before CE even in patients with s CD .