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Is surgery necessary for patients with hepatic angiomyolipoma? Retrospective analysis from eight C hinese cases
Author(s) -
Yang Litao,
Xu Zhiyuan,
Dong Ruizeng,
Fan Jun,
Du Yian,
Zhang Yunli,
Wang Xinbao,
Cheng Xiangdong,
Guo Jianmin
Publication year - 2013
Publication title -
journal of gastroenterology and hepatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.214
H-Index - 130
eISSN - 1440-1746
pISSN - 0815-9319
DOI - 10.1111/jgh.12289
Subject(s) - medicine , asymptomatic , angiomyolipoma , biopsy , radiology , lesion , retrospective cohort study , surgery , kidney
Background and Aim Hepatic angiomyolipoma ( AML ) is a rare, hepatic mesenchymal neoplasm. Its preoperative diagnosis is very difficult, and the treatment is still controversial. The aim is to summarize experience in diagnosis and management of hepatic AML from a cancer center. Methods We retrospectively reviewed the clinical presentation, histopathological, features and treatment of the tumors encountered at our institute from J anuary 2000 to D ecember 2012. Results The patients included six females and two males, with female preponderance. Six patients are asymptomatic. Laboratory tests lack specificity. Combining imaging modality, only one patient obtained the accurate diagnosis of hepatic AML and was confirmed by fine‐needle aspiration biopsy combined with homatropine methylbromide‐45 staining. All other patients received hepatic resection. There was no tumor recurrence or increase of tumor size within the follow‐up period. Conclusion We suggest fine‐needle aspiration combined with homatropine methylbromide‐45 staining should be performed in all patients who are asymptomatic and without serological abnormalities. Surgical resection might be considered only if the malignant potential of the lesion cannot be ruled out or the tumor size is increasing during observation.