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Gastroesophageal Reflux Disease Questionnaire ( GerdQ ) in real‐world practice: A national multicenter survey on 8065 patients
Author(s) -
Bai Yu,
Du Yiqi,
Zou Duowu,
Jin Zhendong,
Zhan Xianbao,
Li ZhaoShen,
Yang Yunsheng,
Liu Yulan,
Zhang Shutian,
Qian Jiaming,
Zhou Liya,
Hao Jianyu,
Chen Dongfeng,
Fang Dianchun,
Fan Daiming,
Yu Xiaofeng,
Sha Weihong,
Nie Yuqiang,
Zhang Xiaofeng,
Xu Hong,
Lv ghua,
Jiang Bo,
Zou Xiaoping,
Fang Jingyuan,
Fan Jiangao,
Li Yan,
Chen Weichang,
Wang Bangmao,
Zou Yiyou,
Li Youming,
Sun Mingjun,
Chen Qikui,
Chen Minhu,
Zhao Xiaoyan
Publication year - 2013
Publication title -
journal of gastroenterology and hepatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.214
H-Index - 130
eISSN - 1440-1746
pISSN - 0815-9319
DOI - 10.1111/jgh.12125
Subject(s) - reflux , medicine , gerd , reflux esophagitis , disease , gastroenterology , esophagitis
Background and Aim Recently, Gastroesophageal Reflux Disease Questionnaire ( GerdQ ) has been developed for diagnosis of GERD . However, no study investigated its value in real‐world practice. This study aimed to investigate whether GerdQ can be used for diagnosis of GERD in C hina. Methods A national multicenter survey was undertaken; all patients who underwent first diagnostic upper endoscopy for upper gastrointestinal ( GI ) symptoms were included. Data including the gender, age, symptoms, and endoscopic findings were prospectively recorded. The GerdQ score was measured before endoscopic procedure. Results Totally, 8065 patients were included. One thousand four hundred and thirty‐five patients (17.8%) had reflux esophagitis. Among them, 620 (43.2%) patients' GerdQ score was ≥ 8. For 2025 patients with GerdQ ≥ 8, 620 (30.6%) were found to have reflux esophagitis, but the remaining 69.4% (1405/2025) were normal. Proportions of patients with reflux esophagitis increased in cut‐off range from 3–18 for GerdQ . However, 22.2% of the patients with a GerdQ score ≤ 2 also had reflux esophagitis. Twenty‐eight (0.3%) patients were diagnosed to have upper GI malignancies, and 10 out of these 28 (35.7%) patients' GerdQ score was ≥ 8. Conclusions The study suggests the proportions of C hinese patients with reflux esophagitis rise up with the increase of GerdQ score, and GerdQ may be used for diagnosis of GERD . However, low GerdQ score cannot exclude the possibility of reflux esophagitis. A minority of C hinese patients has high GerdQ score but is diagnosed with malignancies, even in the absence of alarm features.