Premium
Nutraceutical extracts from some endemic Onosma ( O. ci rcinnata , O. bornmuelleri , and O. angustissima ) species: LC–ESI‐MS/MS–based polyphenol profile, antioxidant and enzyme inhibition activities
Author(s) -
Sarikurkcu Cengiz,
Sahinler Saliha Seyma,
Ozer Mehmet Sabih,
Sihoglu Tepe Arzuhan
Publication year - 2021
Publication title -
journal of food processing and preservation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.511
H-Index - 48
eISSN - 1745-4549
pISSN - 0145-8892
DOI - 10.1111/jfpp.15709
Subject(s) - tyrosinase , chemistry , abts , antioxidant , dpph , polyphenol , traditional medicine , chlorogenic acid , food science , biochemistry , enzyme , medicine
This study aimed to determine the chemical composition of methanol extracts from Onosma circinnata , Onosma bornmuelleri , and Onosma angustissima and to investigate their antioxidant and enzyme inhibitory activities. Spectrophotometric analysis showed that the extracts were found to be rich in chlorogenic acid, luteolin 7‐glucoside, rosmarinic acid, and apigenin 7‐glucoside. While O. bornmuelleri showed the highest activity in DPPH, ABTS, and FRAP tests, O . circinnata was more effective in CUPRAC, phosphomolybdenum, and ferrous ion chelating tests. While O. angustissima showed significant inhibitory activities on AChE, BChE, and tyrosinase, O. bornmuelleri and O . circinnata showed the highest inhibitory activities on α‐amylase and α‐glucosidase. It was concluded that O . circinnata and O. bornmuelleri are effective antioxidant agents and O. angustissima can be considered as an alternative agent in the medical and cosmetic industries due to its ChE and tyrosinase inhibitory activities. Novelty impact statement Biological activities of Onosma species were brought to the literature for the first time with this study. O. circinnata showed remarkable antioxidant activity. O. angustissima exhibited the highest AChE, BChE and tyrosinase inhibitory activity.