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In vivo study of viral haemorrhagic septicaemia virus and infectious pancreatic necrosis virus coexistence in Senegalese sole ( Solea senegalensis )
Author(s) -
LópezVázquez C,
Alonso M C,
Dopazo C P,
Bandín I
Publication year - 2017
Publication title -
journal of fish diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.819
H-Index - 85
eISSN - 1365-2761
pISSN - 0140-7775
DOI - 10.1111/jfd.12585
Subject(s) - superinfection , biology , coinfection , virology , virus , infectious pancreatic necrosis virus , viral interference , microbiology and biotechnology , viral replication
Abstract The effect of IPNV ‐ VHSV coinfection and superinfection on the mortality caused by both viruses in Senegalese sole has been analysed. No effect was observed after coinfection. However, a clear viral interference was recorded between a primary IPNV and a subsequent VHSV infection, which led to a survival increase in the infected sole of 50% points when compared with fish infected only with VHSV . The significantly higher Mx transcriptional values in the fish pre‐exposed to IPNV (at least at first days after superinfection) and the increased daily mortality when low Mx transcriptional levels were recorded suggest that Mx may be involved in the protective effect against VHSV infection. However, in fish subjected to VHSV primary/ IPNV secondary infection, no interference was observed.