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Hypoglycemic and antioxidant effects of five commercial turmeric ( Curcuma longa ) supplements
Author(s) -
GuerreroRomero Fernando,
SimentalMendía Luis E.,
MartínezAguilar Gerardo,
SánchezMeraz Miguel A.,
GamboaGómez Claudia I.
Publication year - 2020
Publication title -
journal of food biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.507
H-Index - 47
eISSN - 1745-4514
pISSN - 0145-8884
DOI - 10.1111/jfbc.13389
Subject(s) - curcuma , antioxidant , curcumin , lipid peroxidation , chemistry , food science , traditional medicine , starch , amylase , pharmacology , biochemistry , enzyme , medicine
We evaluate the hypoglycemic and antioxidant effects of five commercial turmeric ( Curcuma longa ) supplements: (1) bulk samples, (2) turmeric root from India, (3) curcuma turmeric Pronat ® , (4) turmeric & black pepper Swanson ® , and (5) C3 complex ® turmeric curcumin. Glucose diffusion and enzymatic starch digestion assays, using α‐amylase and α‐glucosidase, were performed. The antioxidant activity of turmeric supplements was measured through lipid peroxidation inhibition and the scavenging radical assay. A starch dose of 102 mg/Kg of body weight (equivalent to 1 g/day in humans) was used to perform the oral starch tolerance test (OSTT) in Wistar male rats. All turmeric supplements decreased glucose diffusion and α‐glucosidase enzyme activity, and inhibited lipid peroxidation. The rats that received bulk samples and CT showed significantly lower glucose levels than rats receiving acarbose and those of negative control group. Our results show that biological activities of turmeric supplements vary according to the commercial presentation. Practical applications The study results suggest that the hypoglycemic and antioxidant effects of five commercial turmeric supplements vary among them. The information provided would be useful to physicians and individuals using these supplements.