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Digestive abilities, amino acid transporter expression, and metabolism in the intestines of piglets fed with spermine
Author(s) -
Liu Guangmang,
Mo Weiwei,
Cao Wei,
Jia Gang,
Zhao Hua,
Chen Xiaoling,
Wu Caimei,
Zhang Ruinan,
Wang Jing
Publication year - 2020
Publication title -
journal of food biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.507
H-Index - 47
eISSN - 1745-4514
pISSN - 0145-8884
DOI - 10.1111/jfbc.13167
Subject(s) - spermine , spermidine , putrescine , maltase , metabolism , biochemistry , biology , digestion (alchemy) , amino acid , sucrase , medicine , chemistry , endocrinology , enzyme , chromatography
This study evaluated the effects of spermine supplementation on the digestion, transport, and metabolism of nutrients in the jejuna of piglets. Of the 80 piglets examined, 40 received 0.4 mmol/kg body weight spermine, and the other half were randomly distributed such that the restricted nutrient intake supplemented with the saline solution for 7 hr and 3, 6, or 9 days in pairs. Spermine supplementation increased the lipase and trypsin activities ( p < .05), and spermine increased the mRNA levels of maltase, sucrase, and aminopeptidase N (APN) but decreased the lactase gene expression ( p < .05). Moreover, spermine increased the mRNA expression levels of amino acid transporters ( p < .05). Spermine increased the jejunum glycerolphosphocholine, lipid, and taurine levels and decreased the choline and amino acids levels ( p < .05). In summary, spermine can promote the digestion, transport, and metabolism of nutrients in piglets. Practical applications Meat, fish, dairy products, and fruits contain polyamines (i.e., spermine, spermidine, and putrescine). Spermine plays an important role in the cell proliferation, growth, and differentiation, and spermine supplementation can improve the growth of broilers, growth performance of early weaning piglets, and intestinal maturation. The results of this study suggest that spermine can improve the digestion, transport, and metabolism of nutrients in piglets.