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Molecular hydrogen enhances osteogenesis in Danio rerio embryos
Author(s) -
Carnovali Marta,
Mariotti Massimo,
Banfi Giuseppe
Publication year - 2021
Publication title -
journal of fish biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.672
H-Index - 115
eISSN - 1095-8649
pISSN - 0022-1112
DOI - 10.1111/jfb.14670
Subject(s) - danio , zebrafish , embryo , biology , in vivo , anabolism , microbiology and biotechnology , anatomy , genetics , endocrinology , gene
Molecular hydrogen (H 2 ) has been reported to have important biological effects on bone tissue in several in vitro and in vivo models. Danio rerio (zebrafish) embryo is a good model to study osteogenesis because of its transparency, size and rapid development. In zebrafish embryo, hydrogen‐rich water (HRW) does not affect vitality or growth rate up to 15%. In addition, 7% HRW treatment enhances zebrafish embryo osteogenesis, increasing the vertebral mineralization rate. In conclusion, we demonstrated the beneficial effects of hydrogen on anabolic bone functions in vivo .