Molecular hydrogen enhances osteogenesis in  Danio rerio  embryos | Zendy

Carnovali Marta | Zendy; Mariotti Massimo | Zendy; Banfi Giuseppe | Zendy

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Molecular hydrogen enhances osteogenesis in Danio rerio embryos

Author(s) -

Carnovali Marta,

Mariotti Massimo,

Banfi Giuseppe

Publication year - 2021

Publication title -

journal of fish biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.672

H-Index - 115

eISSN - 1095-8649

pISSN - 0022-1112

DOI - 10.1111/jfb.14670

Subject(s) - danio , zebrafish , embryo , biology , in vivo , anabolism , microbiology and biotechnology , anatomy , genetics , endocrinology , gene

Molecular hydrogen (H 2 ) has been reported to have important biological effects on bone tissue in several in vitro and in vivo models. Danio rerio (zebrafish) embryo is a good model to study osteogenesis because of its transparency, size and rapid development. In zebrafish embryo, hydrogen‐rich water (HRW) does not affect vitality or growth rate up to 15%. In addition, 7% HRW treatment enhances zebrafish embryo osteogenesis, increasing the vertebral mineralization rate. In conclusion, we demonstrated the beneficial effects of hydrogen on anabolic bone functions in vivo .

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