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Effect of topical application of nanoencapsulated eugenol on dental sensitivity reduction after in‐office dental bleaching: a randomized, triple‐blind clinical trial
Author(s) -
Vilela Ana Paula,
Rezende Márcia,
Terra Renata Maria Oleniki,
Silva Karine Letícia,
Sutil Elisama,
Calixto Abraham L.,
Reis Alessandra,
Loguercio Alessandro,
Farago Paulo Vitor
Publication year - 2021
Publication title -
journal of esthetic and restorative dentistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.919
H-Index - 60
eISSN - 1708-8240
pISSN - 1496-4155
DOI - 10.1111/jerd.12728
Subject(s) - mcnemar's test , tooth sensitivity , dentistry , medicine , carbamide peroxide , visual analogue scale , placebo , anesthesia , mathematics , enamel paint , statistics , alternative medicine , pathology
Purpose This randomized, split‐mouth, triple‐blind clinical study evaluated the effect of application of nanoencapsulated eugenol (NE) on the absolute risk and intensity of tooth sensitivity (TS) resulting from in‐office bleaching. Methods Fifty‐six patients received a NE in one hemiarch and a placebo gel in the other hemiarch, determined by random sequence, before in‐office bleaching. A visual analogue scale (VAS) (0–10) and a numeric rating scale (NRS) (0–4) were used to record TS during bleaching and 1 and 48 h after bleaching. The tooth color was performed from baseline to 2 weeks after bleaching with shade guides (ΔSGU) and a spectrophotometer (∆E ab , ∆E 00, and WI D ). The TS was assessed through the McNemar test (α = 0.05) and by the Wilcoxon signed‐rank test (NRS) and paired t ‐test (VAS). The paired test‐t was employed to compare the color changes (ΔSGU and ΔE ab , ∆E 00, and WI D ). The significance level was 5%. Results No statistically significant difference was found in the absolute risk or intensity of TS between both groups ( p > 0.05). A significant color change was observed in both groups ( p > 0.05). Conclusion Administration of the gel containing NE before the in‐office dental bleaching did not reduce the TS and did not interfere in the bleaching effect. Clinical relevance statement The use of desensitizing gel containing NE did not reduce in‐office bleaching‐induced tooth sensitivity.