Premium
Is interdental papilla filling using hyaluronic acid a stable approach to treat black triangles? A systematic review
Author(s) -
Ficho Ana Carolina,
Souza Faloni Ana Paula,
Pennisi Pedro Rogério Camargo,
Borges Lucas Gabriel França,
Macedo Bernadino Ítalo,
Paranhos Luiz Renato,
Queiroz Thallita Pereira,
Santos Pâmela Letícia
Publication year - 2021
Publication title -
journal of esthetic and restorative dentistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.919
H-Index - 60
eISSN - 1708-8240
pISSN - 1496-4155
DOI - 10.1111/jerd.12694
Subject(s) - medicine , major duodenal papilla , inclusion and exclusion criteria , checklist , web of science , hyaluronic acid , sample size determination , dentistry , interdental consonant , orthodontics , meta analysis , mathematics , surgery , biology , statistics , pathology , anatomy , paleontology , alternative medicine
Abstract Purpose To evaluate the stability of interdental papilla filling using hyaluronic acid (HA) to treat black triangles in esthetic regions. Methods The protocol was registered in PROSPERO. Six databases (PubMed, Scopus, Embase, Lilacs, SciELO, and Web of Science) were used as primary search sources, and OpenGrey and OpenThesis were used to capture the “gray literature.” Only before‐after studies were included. The JBI Checklist assessed the risk of bias. Only four studies met the inclusion criteria and were considered for the analyses. The studies were published from 2010 to 2016. All studies presented a low risk of bias. Considering the studies do not have control groups, a weighted average by sample size was calculated to obtain a general estimate of the percentage of papillary filling after 6 months and the number of HA applications. Results The studies showed the percentage of papillary reconstruction after 6 months of application, the weighted average by sample size was 77.41% (SD = 20.68), with an average number of applications of 3.17 (SD = 0.31). Conclusion The application of HA may be used to repair anesthetic defects in the papilla. Clinical significance Interdental papilla reconstruction with injectable HA is an option of nonsurgical treatment for interdental papilla deficiencies. However, there is still concern about the quality of the evidence available, considering that studies with different experimental designs can produce contradictory results. Moreover, further understanding is required on the stability of tissue gain promoted by HA in black triangles.