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A novel carbamide peroxide polymeric nanoparticle bleaching gel: Color change and hydrogen peroxide penetration inside the pulp cavity
Author(s) -
Favoreto Michael W.,
Madureira Mariniella P.,
Hass Viviane,
Maran Bianca M.,
Parreiras Sibelli O.,
Borges Christiane P. F.,
Reis Alessandra,
Loguercio Alessandro D.
Publication year - 2021
Publication title -
journal of esthetic and restorative dentistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.919
H-Index - 60
eISSN - 1708-8240
pISSN - 1496-4155
DOI - 10.1111/jerd.12652
Subject(s) - hydrogen peroxide , carbamide peroxide , penetration (warfare) , chemistry , pulp (tooth) , nuclear chemistry , nanoparticle , dentistry , materials science , nanotechnology , biochemistry , medicine , mathematics , operations research
Objective This study evaluated the hydrogen peroxide (HP) penetration inside the pulp cavity and the color change of teeth submitted to the 15% carbamide peroxide (CP) nanoparticle bleaching gel at several application times. Materials and methods Premolars were divided into nine groups (n = 6) according to 15% CP bleaching agents (nanoparticle and commercial) and to application times (15, 30, 45, and 60 minutes). A negative control was exposed to ultra‐purified water. After a whitening procedure, the HP concentration (μg/mL) inside the pulp cavity was assessed via spectrophotometry. The color change (Δ E * and Δ E 00*) was evaluated with a spectrophotometer. Data were analyzed via two‐way ANOVA and Tukey ( α = 0.05). Results A lower concentration of HP was detected for CP nanoparticle gel after 30 and 45 minutes of whitening procedure ( P = .001). The bleaching groups promoted a higher color change (Δ E * and Δ E 00*) regardless of the application time ( P = .0001). Conclusions The CP nanoparticle gel reduced HP inside the pulp cavity, and showed effective bleaching compared with CP commercial gel. Clinical significance Using 15% carbamide peroxide nanoparticle bleaching gel decreased the HP penetration inside the pulp cavity and may decrease bleaching‐induced tooth sensitivity in at‐home bleaching.