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The interactive effects between air pollution and meteorological factors on the hospital outpatient visits for atopic dermatitis in Beijing, China: a time‐series analysis
Author(s) -
Guo Q.,
Xiong X.,
Liang F.,
Tian L.,
Liu W.,
Wang Z.,
Pan X.
Publication year - 2019
Publication title -
journal of the european academy of dermatology and venereology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.655
H-Index - 107
eISSN - 1468-3083
pISSN - 0926-9959
DOI - 10.1111/jdv.15820
Subject(s) - medicine , beijing , quartile , environmental health , atopic dermatitis , outpatient visits , air pollution , pollutant , air pollutants , poisson regression , china , demography , confidence interval , health care , geography , immunology , chemistry , population , archaeology , organic chemistry , sociology , economic growth , economics
Background The prevalence of atopic dermatitis (AD) dramatically increased over these years and environmental factors were considered as potential contributors towards these trends. Objective This study aimed to explore several major environmental exposures, including air pollution, temperature and relative humidity, in order to identify potential modifiable risk factors and their interactive effects on AD. Methods We applied a bivariate response surface model and stratification model based on time‐series Poisson generalized additive models to examine the interactive effects of air pollution and meteorological factors on AD. Results A total of 64 987 outpatient visits for AD were recorded from 1 January 2013 to 31 December 2017. Interactive effects were found between air pollutants and meteorological factors. Enhanced positive associations between pollutants and outpatient visits for AD were found at the highest quartile temperature level. A 10 μg/m 3 increase in PM 2.5 , PM 10 , NO 2 and SO 2 were associated with 0.42% (95% CI: 0.16–0.67%), 0.34% (95% CI: 0.15–0.54%), 1.11% (95% CI: 0.38–1.84%) and 1.06% (0.21–1.93%) increase in outpatient visits for AD at the highest quartile temperature level. Conclusion That effects of air pollutants on AD can be modified by meteorological factors, with enhanced effects on hot days.