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Onychoscopy of non‐infectious nail abnormalities in patients after allogeneic haematopoietic stem cell transplantation
Author(s) -
SzlauerStefańska A.,
KamińskaWinciorek G.,
Giebel S.
Publication year - 2019
Publication title -
journal of the european academy of dermatology and venereology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.655
H-Index - 107
eISSN - 1468-3083
pISSN - 0926-9959
DOI - 10.1111/jdv.15357
Subject(s) - medicine , nail (fastener) , dermatology , transplantation , stem cell , disease , presentation (obstetrics) , hematopoietic stem cell transplantation , nail disease , pathology , surgery , paronychia , materials science , biology , metallurgy , genetics
Nail abnormalities after allogeneic haematopoietic stem cell transplantation procedure (alloHSCT) are often reported. Usually, they are related to chronic graft‐versus‐host disease (cGvHD). So far, only clinical manifestations of selected nail abnormalities have been described, without the presentation of dermoscopic images. In this article, we present morphologic and dermoscopic manifestations of potential non‐infectious nail abnormalities in patients after alloHSCT procedure based on reviewed literature and our own experience with dermoscopic iconography. In majority of studies published till now, nail changes are not connected to severity of other cGvHD symptoms; however, e.g. the presence of pterygium inversum unguis may be an indicator of lung dysfunction. As nail changes may be an early sign of cGvHD and always present in association with other manifestations, routine clinical assessment should include nails examination. Knowledge of possible presentation of nail involvement after alloHSCT may be valuable for treating physician.