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Prevalence of and risk factors for dermatoporosis: a prospective observational study of dermatology outpatients in a Finnish tertiary care hospital
Author(s) -
Kluger N.,
Impivaara S.
Publication year - 2019
Publication title -
journal of the european academy of dermatology and venereology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.655
H-Index - 107
eISSN - 1468-3083
pISSN - 0926-9959
DOI - 10.1111/jdv.15240
Subject(s) - medicine , concomitant , odds ratio , observational study , diabetes mellitus , prospective cohort study , kidney disease , dermatology , pediatrics , endocrinology
Background Dermatoporosis describes the cutaneous signs and complications related to chronic cutaneous fragility related to ageing, chronic sun exposure and long‐term use of topical and systemic corticosteroids. Chronic renal failure may be an additional cofactor. The prevalence of dermatoporosis is estimated around 32–37% in France among the elderly. Objective We evaluated the prevalence of dermatoporosis and its risk factors in outpatients who attended a consultation in the department of dermatology of Helsinki University Central Hospital. Methods A prospective observational study of 176 consecutive outpatients aged 60 years and older, who attended a consultation in the department of dermatology of Helsinki University Central Hospital. Data collection included age, gender, reason for consultation, local or systemic corticosteroid therapy, antiplatelet drugs and anticoagulant therapy, diabetes and chronic kidney failure (glomerular filtration rate < 60 mL/min/m 2 ). The presence of dermatoporosis, location on the body and staging were collected. Results 30.7% presented dermatoporosis. Lesions were mainly located on the upper limbs (94%), and stage I was the most frequent (75.9% of the cases). Multivariate analysis revealed that dermatoporosis was significantly associated with ultrapotent topical corticosteroids (odds ratio ( OR ) 5.34, 95% CI 1.85–15.43, P = 0.002), oral corticosteroids ( OR 3.22, 95% CI 1.18–8.80, P = 0.022), concomitant corticosteroid therapy, anticoagulant and chronic renal failure ( OR 4.02, 95% CI 1.34–12.01, P = 0.013) and age ( OR 1.05, 95% CI 1.01–1.10, P = 0.016). Patients with bullous pemphigoid were those with the highest prevalence of dermatoporosis in our cohort (64%). Conclusion Acknowledging the selection bias in our study, the prevalence of dermatoporosis in a dermatology consultation in Finland seems as frequent as in France. These results prompt us to weigh the indications of long‐term corticosteroids use in frail elderly patients.