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Fat removal using a new cryolipolysis device: a retrospective study of 418 procedures
Author(s) -
Naouri M.
Publication year - 2017
Publication title -
journal of the european academy of dermatology and venereology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.655
H-Index - 107
eISSN - 1468-3083
pISSN - 0926-9959
DOI - 10.1111/jdv.13899
Subject(s) - medicine , citation , library science , computer science
was considered of positive personal value for 23 (69.7%) selfreported FLG mutation carriers and 16 (59.3%) wild-type carriers (P = 0.40). Also, 23 (65.7%) of self-reported FLG mutation carriers reported that their understanding of AD pathogenesis had improved significantly from knowing their filaggrin genotype as compared to 5 (19.2%) of self-reported wild-type carriers (P < 0.001). The filaggrin genotype was of significant importance in relation to treatment of AD in 15 (42.9%) self-reported FLG mutations carriers compared to 5 (19.2%) self-reported wild-type group carriers (P = 0.05). However, surprisingly, improvement in skin care habits was similar in self-reported FLG mutation and wild-type carriers (9 (25.7%) vs. 7 (25.9%), P = 0.99). For example, only nine (26.5%) FLG mutation carriers vs. six (22.2%) wild-type carriers (P = 0.70) increased their use of emollient. We have no explanation for this discrepancy, but speculate that it is difficult to change treatment habits. This study had limitations. The sample size was small, but reflected the patients who had been seen in the department at the time. The quality of the provided filaggrin information was unequal for all study patients, with a high flow of residents and interns through the clinic, but this setup is likely to reflect real life. To better assess the value of genotyping, a randomized controlled study is required. In conclusion, although patients with self-reported FLG mutations had significantly better understanding of their AD pathogenesis compared to wild type carriers, surprisingly, this information did not result in an increased use of emollients or improvement in skin care habits.