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Prognostic clinical factors associated with remission and relapse in bullous pemphigoid
Author(s) -
Lee J.H.,
Kim T.H.,
Park S.H.,
Han K.,
Kim S.C.
Publication year - 2017
Publication title -
journal of the european academy of dermatology and venereology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.655
H-Index - 107
eISSN - 1468-3083
pISSN - 0926-9959
DOI - 10.1111/jdv.13839
Subject(s) - medicine , bullous pemphigoid , multivariate analysis , complete remission , retrospective cohort study , proportional hazards model , surgery , chemotherapy , immunology , antibody
Background Prognostic factors for remission and relapse of bullous pemphigoid ( BP ) remain uncertain. Objective To evaluate clinical factors associated with remission and relapse in Korean patients with BP . Methods A retrospective analysis was conducted of 174 patients diagnosed with BP between 1993 and 2014 at Gangnam Severance Hospital in Seoul, Korea. Results Of the 174 identified patients, 131 (75.29%) achieved remission after a mean treatment duration of 393.69 days. Prognostic factors for remission were older age (≥70 years) and the absence of an admission history. Of 131 patients who achieved remission, 40 patients (30.53%) experienced relapse after a mean duration of 335.65 days. However, no statistically significant factors were predictive of relapse by multivariate analysis. Conclusions This study suggests BP patients who are older and have no admission history tend to achieve remission.