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Non‐cosmetic dermatological uses of botulinum neurotoxin
Author(s) -
Forbat E.,
Ali F.R.,
AlNiaimi F.
Publication year - 2016
Publication title -
journal of the european academy of dermatology and venereology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.655
H-Index - 107
eISSN - 1468-3083
pISSN - 0926-9959
DOI - 10.1111/jdv.13772
Subject(s) - medicine , botulinum neurotoxin , dermatology , neurotoxin , microbiology and biotechnology , toxin , biology
Botulinum neurotoxin (Bo NT ) is renowned for its inhibitory effects on the neuromuscular junction. The evidence for its use in cosmetic dermatology and in non‐dermatological indications is well established. We have systemically analysed the evidence for the non‐cosmetic dermatological uses of Bo NT . This review presents the many small studies showing promising results for the use of Bo NT in a multitude of dermatological diseases, including (but not limited to) hyperhidrosis, Darier's disease, Hailey–Hailey disease, pompholyx and hidradenitis suppurativa. There is, however, the need for larger, double‐blinded randomized control trials against established treatments to cement the evidence base underlying the use of Bo NT in dermatology.