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Contact sensitization in patients with suspected cosmetic intolerance: results of the IVDK 2006–2011
Author(s) -
Dinkloh A.,
Worm M.,
Geier J.,
Schnuch A.,
Wollenberg A.
Publication year - 2015
Publication title -
journal of the european academy of dermatology and venereology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.655
H-Index - 107
eISSN - 1468-3083
pISSN - 0926-9959
DOI - 10.1111/jdv.12750
Subject(s) - medicine , cosmetics , lanolin , sensitization , dermatology , allergic contact dermatitis , allergen , allergy , contact dermatitis , immunology , pathology , chemistry , organic chemistry
Background Ingredients of leave‐on cosmetics and body care products may sensitize. However, not every case of cosmetic intolerance is due to contact sensitization. Objective To describe the frequency of contact sensitization due to cosmetics in a large clinic population, and a possible particular allergen pattern. Methods Retrospective analysis of data from the Information Network of Departments of Dermatology, 2006–2011. Results Of 69 487 patients tested, ‘cosmetics, creams, sunscreens’ was the only suspected allergen source category in 10 124 patients (14.6%). A final diagnosis ‘allergic contact dermatitis’ was stated in 2658 of these patients (26.3%).Compared to a control group, there were significantly more reactions to fragrance mixes I and II, balsam of Peru, methylchloroisothiazolinone/methylisothiazolinone ( MCI / MI ) and lanolin alcohols. No special pattern of fragrance sensitization could be identified. Among the preservatives, MI was by far the leading allergen, while sensitization to other widely used compounds like parabens or phenoxyethanol was rare. Conclusions True allergic reactions to cosmetic ingredients are rarer than generally assumed. Limitation of exposure to MI in leave‐on cosmetics and body care products is urgently needed.