Narrowband ultraviolet B phototherapy in combination with other therapies for vitiligo: mechanisms and efficacies | Zendy

Yazdani Abyaneh M. | Zendy; Griffith R.D. | Zendy; FaltoAizpurua L. | Zendy; Nouri K. | Zendy

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Narrowband ultraviolet B phototherapy in combination with other therapies for vitiligo: mechanisms and efficacies

Author(s) -

Yazdani Abyaneh M.,

Griffith R.D.,

FaltoAizpurua L.,

Nouri K.

Publication year - 2014

Publication title -

journal of the european academy of dermatology and venereology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.655

H-Index - 107

eISSN - 1468-3083

pISSN - 0926-9959

DOI - 10.1111/jdv.12619

Subject(s) - vitiligo , medicine , ultraviolet b , dermatology , calcineurin , disease , population , ultraviolet therapy , psoriasis , transplantation , environmental health

Vitiligo is a disorder of pigmentation affecting about 1% of the global population. It is a psychologically devastating disease with suboptimal treatment options. Narrowband ultraviolet B ( NB ‐ UVB ) phototherapy has become a first‐line choice for treating generalized disease. In recent years, topical calcineurin inhibitors, vitamin D analogues, antioxidant agents and other therapies have been combined with NB ‐ UVB to improve its efficacy. This article will address what is known about the mechanisms of action of these treatments and how they may complement NB ‐ UVB on a cellular level, as well as offer a comprehensive, evidence‐based review of clinical outcomes with combination therapies.

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