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Scabies increased the risk of chronic kidney disease: a 5‐year follow‐up study
Author(s) -
Chung S.D.,
Wang K.H.,
Huang C.C.,
Lin H.C.
Publication year - 2014
Publication title -
journal of the european academy of dermatology and venereology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.655
H-Index - 107
eISSN - 1468-3083
pISSN - 0926-9959
DOI - 10.1111/jdv.12099
Subject(s) - medicine , scabies , kidney disease , hazard ratio , diabetes mellitus , population , incidence (geometry) , retrospective cohort study , pediatrics , confidence interval , dermatology , environmental health , endocrinology , physics , optics
Background The most documented complication of scabies has been reported to be infection by group A streptococci, which has in turn been suggested to contribute to the development of glomerulonephritis. Objective This study aimed to investigate the risk of chronic kidney disease ( CKD ) subsequent to scabies utilizing a population‐based dataset in Taiwan. Methods This retrospective matched‐cohort study included 5071 subjects with scabies and 25 355 randomly selected comparison subjects. We individually tracked each subject for a 5‐year period to identify those who subsequently received a diagnosis of CKD during the follow‐up period. Stratified Cox proportional hazards regressions were performed to compute the hazard ratio ( HR ) of CKD during the 5‐year follow‐up period. Results The incidence rate of CKD during the 5‐year follow‐up period was 9.66 (8.51–10.93) per 1,000 person‐years and 6.24 (5.82–6.69) per 1000 person‐years for subjects with and without scabies respectively. The HR for CKD during the 5‐year follow‐up period for subjects with scabies was 1.34 (95% CI = 1.15–1.56) that of comparison subjects after adjusting for monthly income, hypertension, diabetes, obesity, stroke, coronary heart disease, chronic obstructive pulmonary disease, tobacco use disorder, hyperlipidemia and alcohol abuse during the 5‐year follow‐up period. Male subjects with scabies were 1.40 (95% CI = 1.14–1.71) times more likely than comparison subjects to suffer from subsequent CKD , and female study subjects were 1.27 (95% CI = 1.05–1.61) times more likely. Conclusions We concluded that there was an increased risk for CKD among patients suffering from scabies.