Open AccessPredictors of postoperative bleeding after vitrectomy for vitreous hemorrhage in patients with diabetic retinopathy
Author(s) -
Motoda Saori,
Shiraki Nobuhiko,
Ishihara Takuma,
Sakaguchi Hirokazu,
Kabata Daijiro,
Takahara Mitsuyoshi,
Kimura Takekazu,
Kozawa Junji,
Imagawa Akihisa,
Nishida Kohji,
Shintani Ayumi,
Iwahashi Hiromi,
Shimomura Iichiro
Publication year - 2018
Publication title -
journal of diabetes investigation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.089
H-Index - 50
eISSN - 2040-1124
pISSN - 2040-1116
DOI - 10.1111/jdi.12791
Subject(s) - vitrectomy , medicine , diabetic retinopathy , vitreous hemorrhage , perioperative , pars plana , diabetes mellitus , retinopathy , retrospective cohort study , ophthalmology , surgery , anesthesia , visual acuity , endocrinology
Aims/Introduction To clarify the association between perioperative variables and postoperative bleeding in pars plana vitrectomy for vitreous hemorrhage in diabetic retinopathy. Materials and Methods The present retrospective study enrolled 72 eyes of 64 patients who were admitted to Osaka University Hospital between April 2010 and March 2014, and underwent vitrectomy for vitreous hemorrhage as a result of diabetic retinopathy. Results Postoperative bleeding developed in 12 eyes. Using binomial logistic regression analysis, we found that the duration of operation was the only significant variable associated with postoperative bleeding within 12 weeks after vitrectomy. Furthermore, Poisson regression analysis identified fasting blood glucose just before vitrectomy, no treatment with antiplatelet drugs and treatment with antihypertensive drugs, as well as duration of operation, to be significantly associated with the frequency of bleeding within 52 weeks after vitrectomy. Conclusions Long duration of operation can be used to predict bleeding within both 12 and 52 weeks after vitrectomy. In addition, fasting blood glucose just before vitrectomy, no treatment with antiplatelet drugs and treatment with antihypertensive drugs might be risk factors for postoperative bleeding up to 1 year after vitrectomy.