Open AccessAge at natural menopause and risk of diabetes in adult women: Findings from the China Kadoorie Biobank study in the Zhejiang area
Author(s) -
Wang Meng,
Hu RuYing,
Wang Hao,
Gong WeiWei,
Wang ChunMei,
Xie KaiXu,
Chen ZhengMing,
Guo Yu,
Yu Min,
Li LiMing
Publication year - 2018
Publication title -
journal of diabetes investigation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.089
H-Index - 50
eISSN - 2040-1124
pISSN - 2040-1116
DOI - 10.1111/jdi.12775
Subject(s) - medicine , menopause , biobank , odds ratio , diabetes mellitus , confidence interval , logistic regression , demography , china , epidemiology , gerontology , population , type 2 diabetes , environmental health , endocrinology , bioinformatics , law , biology , sociology , political science
Aims/Introduction There has been considerable professional debate on the association between age at menopause and diabetes risk, while the findings are controversial. The present study explored the association between late menopause and the prevalence of diabetes in the Chinese population. Material and Methods The data were part of the baseline survey of China Kadoorie Biobank from Zhejiang Province. A total of 17,076 postmenopausal women were included in the present study. Logistic regression models were used to calculate the adjusted odds ratios and their 95% confidence intervals. Results Of the participating women, 1,288 (7.54%) had type 2 diabetes. In comparison with those with menopause at 46–52 years, women with menopause at a later age (≥53 years) were 1.21‐fold (95% confidence interval 1.03–1.43) more likely to have diabetes. Conclusions The present findings suggested that later age at menopause was associated with an increased prevalence of diabetes.