English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Zendy Plus

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Zendy Tools

Zendy Open

Aims/Introduction  Peroxisome proliferator activated receptor gamma (  PPARG  ) is a nuclear hormone receptor of the ligand‐dependent transcription factor involved in adipogenesis, and a molecular target of the insulin sensitizer, thiazolidinediones. The present study aimed to investigate whether the   PPARG   gene is associated with type 2 diabetes mellitus and its related traits within the population of  W est  B engal,  I ndia.    Materials and Methods  The study participants (200 type 2 diabetes mellitus and 200 normal individuals) were chosen randomly, and the variants were screened by direct sequencing.    Results  The results showed that rs1801282 (odds ratio 0.66; 95% confidence interval 0.15–2.96;  P  = 0.57) and rs3856806 (odds ratio 1.23; 95% confidence interval 0.73–2.06;  P  = 0.44) variants of the   PPARG   gene were not associated with type 2 diabetes mellitus.    Conclusions  The results showed that the   PPARG   gene was not associated with type 2 diabetes mellitus in our study population. As the lack of association might come from the small sample size, further studies with larger sample size are required to verify the present observation.

Role of peroxisome proliferator‐activated receptor gamma gene polymorphisms in type 2 diabetes mellitus patients of W est B engal, I ndia