Open AccessTwenty‐year trend of increasing obesity in young patients with poorly controlled type 2 diabetes at first diagnosis in urban J apan
Author(s) -
Kushiyama Akifumi,
Yoshida Yoko,
Kikuchi Takako,
Suzawa Naoki,
Yamamoto Mayumi,
Tanaka Kentaro,
Okayasu Mineko,
Tahara Tazu,
Takao Toshiko,
Onishi Yukiko,
Kawazu Shoji
Publication year - 2013
Publication title -
journal of diabetes investigation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.089
H-Index - 50
eISSN - 2040-1124
pISSN - 2040-1116
DOI - 10.1111/jdi.12090
Subject(s) - medicine , glycemic , glycated hemoglobin , body mass index , diabetes mellitus , obesity , type 2 diabetes mellitus , type 2 diabetes , cross sectional study , pediatrics , endocrinology , pathology
Abstract Aims/Introduction To investigate trends over the past 20 years for the prevalence of obesity and glycemic control in association with a patient's first hospital visit for type 2 diabetes mellitus. Materials and Methods This was a historical, cross‐sectional, time‐series, single‐center study carried out at M arunouchi H ospital. Data from type 2 diabetic patients who were never treated until their first hospital visit were analyzed for the following periods: 1986–1987 (group A , n = 453), 1996–1997 (group B , n = 547) and 2006–2008 (group C , n = 443). Data on each patient's body mass index ( BMI ), age, untreated duration and glycated hemoglobin levels were also collected. Results Obesity in younger patients (below age 40 years and ages 40–49 years in group C) with poor glycemic control increased over time. Patients with a BMI of <21.0 kg/m 2 or ≥23.0 kg/m 2 showed worse glycemic control than those with a BMI of 21.0–23.0 kg/m 2 in group C . Younger patients had worse glycemic control and shorter untreated durations in group C . A BMI ≥23.0 kg/m 2 was an independent risk factor for glycated hemoglobin levels ≥8.4% in group C , even after correction for sex, age, untreated duration and symptoms. Conclusions In recent years, glycemic control has worsened in young, obese patients in urban Japan. Obesity is rapidly increasing in younger patients, and patients with a BMI ≥23.0 kg/m 2 might be candidates for diabetes screening. This trial was registered with the University Medical Information Network Clinical Trials Registry (no. UMIN5725).