Open AccessMechanism‐based antioxidant therapies promise to prevent diabetic complications?
Author(s) -
Nishikawa Takeshi,
Araki Eiichi
Publication year - 2013
Publication title -
journal of diabetes investigation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.089
H-Index - 50
eISSN - 2040-1124
pISSN - 2040-1116
DOI - 10.1111/jdi.12041
Subject(s) - medicine , diabetes mellitus , lipoic acid , antioxidant , vitamin c , diabetic neuropathy , glycemic , oxidative stress , clinical trial , vitamin e , pharmacology , ascorbic acid , endocrinology , biochemistry , chemistry , food science
Intensive blood glucose control can prevent the initiation and progression of diabetic complications. However, the impacts of intensive therapy against diabetic complications might be limited, because of difficulty in maintaining blood glucose concentrations close to the normal range or other unknown reasons. Thus, another approach based on the elucidation of mechanisms of diabetic complications might be required to prevent the progression of the complications.