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Paediatric viral myocarditis successfully treated with interferon beta‐1b and corticoids
Author(s) -
Canales Siguero Dolores,
GarcíaMuñoz Carmen,
Martínez de la Torre Francisco,
Ferrari Piquero Jose Miguel,
Granados Ruíz Miguel Angel
Publication year - 2021
Publication title -
journal of clinical pharmacy and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.622
H-Index - 73
eISSN - 1365-2710
pISSN - 0269-4727
DOI - 10.1111/jcpt.13357
Subject(s) - medicine , beta (programming language) , viral myocarditis , myocarditis , interferon beta , interferon , virology , immunology , computer science , programming language
What is known and objective In paediatrics, evidence regarding the treatment of viral myocarditis using interferon beta‐1B is restricted to four children older than two years and there are no reported cases of infants. The objective was to describe the efficacy and safety of interferon beta‐1B in two infants under one year of age with viral myocarditis. Case summary Two infants were admitted to the hospital presenting with respiratory symptoms. Echocardiogram showed myocardial damage. Parvovirus‐B19 was detected using a PCR assay, and treatment with interferon beta‐1B was initiated. Six months later, the cardiac function had recovered in both cases. What is new and conclusion This is the first published series of cases of infants less than 1 year of age with viral myocarditis treated with interferon beta‐1B.