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Dexmedetomidine‐induced fever and delirium: A case report
Author(s) -
Straw L. B.,
Dodson C. R.,
Schrift D. S.
Publication year - 2018
Publication title -
journal of clinical pharmacy and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.622
H-Index - 73
eISSN - 1365-2710
pISSN - 0269-4727
DOI - 10.1111/jcpt.12680
Subject(s) - dexmedetomidine , delirium , medicine , sedation , anesthesia , intensive care unit , discontinuation , ards , psychomotor agitation , intensive care medicine , surgery , lung
Summary What is known and objective Dexmedetomidine is a selective alpha‐2 agonist used for sedation in the intensive care unit ( ICU ). Case description A 41‐year‐old woman intubated in the ICU and being treated for acute respiratory distress syndrome ( ARDS ) received dexmedetomidine following successful extubation to treat increasing agitation thought to be secondary to a history of polysubstance abuse. Following initiation of the dexmedetomidine, the patient became febrile as well as increasingly more agitated and delirious. All potential fever or delirium causes were evaluated. Following discontinuation of dexmedetomidine, her fever, agitation and delirium ceased. What is new and conclusion We depict the first known case of dexmedetomidine causing high fevers and delirium.