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Survival without peripheral neuropathy after massive acute arsenic poisoning: Treated by 2,3‐dimercaptopropane‐1‐sulphonate
Author(s) -
Lu P.H.,
Tseng J.C.,
Chen C.K.,
Chen C.H.
Publication year - 2017
Publication title -
journal of clinical pharmacy and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.622
H-Index - 73
eISSN - 1365-2710
pISSN - 0269-4727
DOI - 10.1111/jcpt.12538
Subject(s) - arsenic poisoning , arsenic trioxide , arsenic , medicine , chelation therapy , peripheral neuropathy , surgery , chemistry , organic chemistry , thalassemia , diabetes mellitus , endocrinology
Summary What is known and objective Massive acute arsenic poisoning is rare yet potentially life‐threatening. 2,3‐dimercaptopropane‐1‐sulphonate ( DMPS ) appears to have the appropriate chelating property. However, clinical experience on the use of DMPS in massive arsenic poisoning is limited. Case description A 37‐year‐old woman attempted suicide by ingesting 37.5 g of arsenic trioxide. DMPS was promptly initiated based on history and clinical symptoms. The patient recovered completely, with no complications or side effects of the therapy. What is new and conclusion TDMPS is useful for the treatment of massive acute arsenic poisoning.