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Propofol‐induced acute pancreatitis
Author(s) -
Csomor J.,
Murínová I.,
Broulíková K.,
Kučerka O.,
Sedloň P.,
Jarošek J.,
Urbánek P.,
Zavoral M.
Publication year - 2017
Publication title -
journal of clinical pharmacy and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.622
H-Index - 73
eISSN - 1365-2710
pISSN - 0269-4727
DOI - 10.1111/jcpt.12524
Subject(s) - medicine , acute pancreatitis , propofol , pancreatitis , complication , anesthesia , surgery
Summary What is known and objective Drug‐induced acute pancreatitis comprises only 0.5%‐2% of all cases of acute pancreatitis. Propofol is a potentially dangerous drug that can cause acute pancreatitis, but this complication is extremely rare. Case summary A 57‐year‐old patient developed acute pancreatitis after a planned thyroidectomy. As the common causes of acute pancreatitis were excluded, we believe that the pancreatitis was drug‐induced, in this case by a single dose of propofol administered to the patient during the surgery. What is new and conclusion We present a rare case of propofol‐induced acute necrotising pancreatitis, which is to the best of our knowledge the first fatal case reported in an adult patient.