Premium
Sigmoid‐vaginal fistula during bevacizumab treatment diagnosed by fistulography
Author(s) -
Hayashi C.,
Takada S.,
Kasuga A.,
Shinya K.,
Watanabe M.,
Kano H.,
Takayama T.
Publication year - 2016
Publication title -
journal of clinical pharmacy and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.622
H-Index - 73
eISSN - 1365-2710
pISSN - 0269-4727
DOI - 10.1111/jcpt.12454
Subject(s) - medicine , bevacizumab , fistula , vagina , surgery , colonoscopy , colorectal cancer , rectovaginal fistula , sigmoid colon , vaginal discharge , vaginal cancer , radiology , cervical cancer , cancer , chemotherapy , rectum
Summary What is known and objective There have been several reports describing rectovaginal fistula development after bevacizumab treatment, and these fistulas were diagnosed by CT scan or colonoscopy. We report a case of sigmoid‐vaginal fistula diagnosed by fistulography. Case description The case is a 53‐year‐old woman who was treated for chronic myelogenous leukaemia and gynaecological cancers 8 years previously. At 52 years of age, she was diagnosed with colon cancer and had a partial colectomy performed. One year after surgery, colon cancer recurred, and she was treated with anticancer agents, including bevacizumab. During chemotherapy, she complained of a foul smelling discharge from the vagina. Fistulography revealed a sigmoid‐vaginal fistula. What is new and conclusion This is the first report of vaginal fistulography performed on a patient who was treated with bevacizumab. Fistulography may be useful for detecting sigmoid‐vaginal fistula.