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Is it tinidazole‐induced pancreatitis?
Author(s) -
Hegazi M. O.,
Saleh F.,
John J. E.
Publication year - 2015
Publication title -
journal of clinical pharmacy and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.622
H-Index - 73
eISSN - 1365-2710
pISSN - 0269-4727
DOI - 10.1111/jcpt.12307
Subject(s) - tinidazole , metronidazole , acute pancreatitis , pancreatitis , medicine , drug , gastroenterology , pharmacology , antibiotics , microbiology and biotechnology , biology
Summary What is known and objective Metronidazole is one of the drugs with a well‐recognized potential to rarely cause acute pancreatitis. The relation of other drugs of the 5‐aminoimidazole group (e.g. tinidazole) to acute pancreatitis remains unknown. For the treatment of protozoal infections, tinidazole may be considered as an alternative to metronidazole in cases of intolerability or inadequate response. Case summary We report a case of acute pancreatitis possibly induced by tinidazole. What is new and conclusion Tinidazole may probably cause acute pancreatitis similar to metronidazole. Physicians may occasionally encounter an individual with history of metronidazole‐induced pancreatitis who requires antiprotozoal therapy. We believe it may be safer to choose a drug outside the 5‐aminoimidazole group in this situation.