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Cannabidiol can improve complex sleep‐related behaviours associated with rapid eye movement sleep behaviour disorder in Parkinson's disease patients: a case series
Author(s) -
Chagas M. H. N.,
Eckeli A. L.,
Zuardi A. W.,
PenaPereira M. A.,
SobreiraNeto M. A.,
Sobreira E. T.,
Camilo M. R.,
Bergamaschi M. M.,
Schenck C. H.,
Hallak J. E. C.,
Tumas V.,
Crippa J. A. S.
Publication year - 2014
Publication title -
journal of clinical pharmacy and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.622
H-Index - 73
eISSN - 1365-2710
pISSN - 0269-4727
DOI - 10.1111/jcpt.12179
Subject(s) - cannabidiol , parasomnia , parkinson's disease , rem sleep behavior disorder , rapid eye movement sleep , medicine , sleep (system call) , eye movement , cannabis sativa , psychiatry , sleep disorder , disease , psychology , cannabis , physical medicine and rehabilitation , insomnia , electroencephalography , ophthalmology , botany , computer science , biology , operating system
Summary What is known and objective Cannabidiol ( CBD ) is the main non‐psychotropic component of the C annabis sativa plant. REM sleep behaviour disorder ( RBD ) is a parasomnia characterized by the loss of muscle atonia during REM sleep associated with nightmares and active behaviour during dreaming. We have described the effects of CBD in RBD symptoms in patients with Parkinson's disease. Cases summary Four patients treated with CBD had prompt and substantial reduction in the frequency of RBD ‐related events without side effects. What is new and conclusion This case series indicates that CBD is able to control the symptoms of RBD .