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Bisphenol A in relation to behavior and learning of school‐age children
Author(s) -
Hong SoonBeom,
Hong YunChul,
Kim JaeWon,
Park EunJin,
Shin MinSup,
Kim BoongNyun,
Yoo HeeJeong,
Cho InHee,
Bhang SooYoung,
Cho SooChurl
Publication year - 2013
Publication title -
journal of child psychology and psychiatry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.652
H-Index - 211
eISSN - 1469-7610
pISSN - 0021-9630
DOI - 10.1111/jcpp.12050
Subject(s) - cbcl , child behavior checklist , psychology , developmental psychology , anxiety , association (psychology) , population , clinical psychology , logistic regression , psychiatry , medicine , environmental health , psychotherapist
Background Bisphenol A ( BPA ) has been shown to affect brain and behavior in rodents and nonhuman primates, but there are few studies focusing on its relationship to human neurobehavior. We aimed to investigate the relationship between environmental exposure to BPA and childhood neurobehavior. Methods Urinary BPA concentrations and behavioral and learning characteristics were assessed in a general population of 1,089 children, aged 8–11 years. The main outcome measures were the Child Behavior Checklist ( CBCL ) and the Learning Disability Evaluation Scale ( LDES ). Results Urinary levels of BPA were positively associated with the CBCL total problems score and negatively associated with the learning quotient from the LDES . The linear association with the CBCL anxiety/depression score and the quadratic association with the LDES listening score were significant after correction for multiple comparisons. Conclusions Environmental exposure to BPA might be associated with childhood behavioral and learning development. The results suggest possible nonmonotonic relationships.