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Oral health and changes in lipid profile: A nationwide cohort study
Author(s) -
Song TaeJin,
Kim JinWoo,
Kim Jinkwon
Publication year - 2020
Publication title -
journal of clinical periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.456
H-Index - 151
eISSN - 1600-051X
pISSN - 0303-6979
DOI - 10.1111/jcpe.13373
Subject(s) - medicine , triglyceride , periodontitis , oral hygiene , high density lipoprotein , cholesterol , cohort , dentistry , cohort study , blood lipids , lipid profile , tooth brushing , gastroenterology , brush , toothbrush , electrical engineering , engineering
Abstract Aim We aimed to investigate the association of periodontitis and oral hygiene indicators with changes in blood lipid parameters in a nationwide, population‐based cohort in a longitudinal setting. Materials and methods We included nationwide health screening program participants who underwent oral health examination in 2009‐2010 and follow‐up examinations for lipid profile without exposure to lipid‐lowering agents. Results During the 5.19‐year median follow‐up, 65,078 individuals (mean age at baseline examination: 55.41 ± 7.30 years) underwent 286,218 health examinations. The prevalence of periodontitis was 39%. In the multivariate mixed model analysis, periodontitis and tooth loss were associated with decreased high‐density lipoprotein cholesterol levels (β = −0.0066 mmol/L, standard error = 0.0026, p = .013) and increased triglyceride levels (β=0.0307, mmol/L, standard error = 0.0049, p < .001), respectively. Compared with tooth brushing ≤1 time/day, tooth brushing ≥3 times/day was associated with increased high‐density lipoprotein cholesterol levels (β = 0.0176 mmol/L, standard error = 0.0052, p = .006) and decreased triglyceride levels (β = −0.0285 mmol/L, standard error = 0.0090, p = .001). Conclusions Periodontitis and tooth loss may be attenuating factors for blood high‐density lipoprotein cholesterol and triglyceride levels, respectively. Frequent tooth brushing may improve dyslipidaemia, particularly blood high‐density lipoprotein cholesterol and triglyceride levels. Oral hygiene improvement may reduce the risk of dyslipidaemia.