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Global prevalence of aggressive periodontitis: A systematic review and meta‐analysis
Author(s) -
Bouziane Amal,
Hamdoun Radia,
Abouqal Redouane,
Ennibi Oumkeltoum
Publication year - 2020
Publication title -
journal of clinical periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.456
H-Index - 151
eISSN - 1600-051X
pISSN - 0303-6979
DOI - 10.1111/jcpe.13266
Subject(s) - meta analysis , funnel plot , medicine , publication bias , periodontitis , prevalence , cochrane library , confidence interval , population , medline , study heterogeneity , random effects model , demography , aggressive periodontitis , odds ratio , epidemiology , environmental health , biology , biochemistry , sociology
Aim The prevalence of aggressive periodontitis (AgP) varies considerably between studies. The aim of this meta‐analysis was to estimate, throughout the world, the prevalence of this disease. Materials and Methods Pubmed/Medline, Scopus, Science Direct, EBSCO and Cochrane library were systematically searched up to March 2018. Study selection criteria included cross‐sectional studies reporting prevalence of AgP in non‐specific population and permanent dentition. We assessed risk of bias using the Joanna Briggs Institute tool. A random effect meta‐analysis model was used to estimate the prevalence of AgP. Publication bias was assessed by Begg and Egger's tests and visual aspect of funnel plot. Results A total of 33 articles were included. Pooled prevalence for AgP was 1.6% (95% CI 1.1–2.3). Higher pooled prevalence rates were reported in Africa (4.2%, 95% CI 2.0–7.1) and South America (4.0%, 95% CI 0.9–9.1) compared with Europe (0.1%, 95% CI 0.1–0.2). A pooled prevalence of 1.2%, 95% CI 0.5–2.2 was found in Asia and 0.8%, 95% CI 0.4–1.4 in North America. Heterogeneity between groups was statistically significant ( Q statistic p < .001). Conclusions A relatively high prevalence of AgP was found in Africa. However, the data support the weakness of the definition of this form of periodontal disease. Studies with less heterogeneity are needed to address accurately the prevalence of AgP.