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Obesity as predictive factor of periodontal therapy clinical outcomes: A cohort study
Author(s) -
Suvan Jean,
Harrington Zoe,
Petrie Aviva,
Patel Kalpesh,
Darbar Ulpee,
Donos Nikos,
D'Aiuto Francesco
Publication year - 2020
Publication title -
journal of clinical periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.456
H-Index - 151
eISSN - 1600-051X
pISSN - 0303-6979
DOI - 10.1111/jcpe.13261
Subject(s) - medicine , periodontitis , confounding , obesity , bleeding on probing , clinical attachment loss , body mass index , gastroenterology , dentistry
Aim The study aim was to investigate the predictive role of obesity on clinical response following non‐surgical periodontal therapy in individuals with severe periodontitis. Methods A total of 57 BMI obese and 58 BMI normal non‐smoker adults with periodontitis (defined as probing pocket depths (PPD) of ≥5 mm and alveolar bone loss of >30% with >50% of the teeth affected) received non‐surgical periodontal therapy. Periodontal status was based upon PPD, clinical attachment level (CAL) and full‐mouth bleeding score (FMBS). Mean PPD, percentage sites PPD >4 mm, percentage sites PPD >5 mm and FMBS at 2 and 6 months were outcome variables. Propensity score analysis was used to assess the effect of obesity on outcome variables after adjusting for confounders. Results Statistically significant higher clinical measures (mean PPD, mean percentage of sites with PPD >4 mm, mean percentage of sites with PPD >5 mm and FMBS) were observed in the obese group than the normal group at baseline, 2 and 6 months after therapy ( p < .01). At 2 and 6 months, obesity was associated with worse mean PPD ( p < .05), percentage sites with PPD >4 mm ( p < .05), percentage sites with PPD > 5mm ( p < .05) and FMBS ( p < .01), independent of age, gender, ethnicity or plaque levels. Conclusions Obesity compared to normal BMI status was an independent predictor of poorer response following non‐surgical periodontal therapy.